Saturday, March 31, 2012

Streptomycin



Streptomycin is the drug that include the aminoglycoside. Streptomycin is working by turning off the sensitive bacteria, to stop the manufacture of essential proteins thatbacteria need to survive.

Indications:

To treat tuberculosis (TB) and infections caused by certain bacteria.

Dosage:

1-2 g / day through the muscle (intra muscular) or through a vein (intra-vascular), individed doses.

Side Effects:

Ototoxic effects (can cause ototoxicity that can not be changed, in the form of hearingloss, dizziness, vertigo); renal effects (nephrotoxicity that can be changed, acute renal failure reported to occur usually when other nephrotoxic drugs are also given);neuromuscular effects (inhibition of which produces neuromuscular depression rowand muscular paralysis); hypersensitivity reaction.

Special Instructions:

Ototoxicity and nephrotoxicity are most likely found in geriatric patients and patientswho are dehydrated, in patients receiving high doses or who take medication for a long time, those who also receive or have received other nephrotoxic or ototoxicdrugs. (Note supervision or peak serum concentration and serum concentration / MICratio in this patient)

Use with caution in patients with a condition associated with muscle weakness (eg,myasthenia gravis, Parkinson’s disease), patients who have renal dysfunction,vestibular or cochlear damage.

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