Acipimox is a derivative of niacin that are useful as hypolipidemic agents. Acipimox used in low doses. These drugs inhibit the manufacture and secretion of VLDL triglycerides heart.
Indications:
To reduce the LDL cholesterol (low-density lipoproteins) and raise HDL (high-density lipoprotein).
Dose:
250 mg by mouth (orally), 2-3 times the maximum daily dose : 1250 mg / day
Side effects:
redness, itching, rash, GI effects (heartburn, epigastric pain, drunkenness, etc.), headaches.
Special Instructions:
Not recommended in patients with peptic ulcer . Use with caution in patients with renal impairment.
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