Digoxin digitalis is obtained from the leaves of plants (leaves used as medicine strengthens the heart). Digoxin helps make the heart beat stronger and with more regular rhythm.Indications:
To treat congestive heart failure, are also used to treat atrial fibrillation, heart rhythm disturbances in the atria (the upper porch of heart that allows blood to flow to the heart).
Dosage:
62.5-250 micrograms orally (by mouth), 1 time a day
Side Effects:
Side effects are usually due to poisoning or overdose of Digoxin and Digoxin is usually well tolerated when administered in accordance with the recommended dose for congestive heart failure (CHF).
Digoxin poisoning: Effect of GI (N / V, anorexia, diarrhea, abdominal pain) is usually the first signs of toxicity Digoxin; Other signs of toxicity Digoxin: CNS effects (headache, fatigue, pain in the face, weakness, dizziness, mental confusion), vision disturbances (blurred vision, impaired color); toxins can cause serious CV effects (worsening heart failure (HF), arrhythmias, discovered the existence of conduction).
Hypokalaemia may predispose a person to Digoxin toxicity.
Hypersensitivity reactions are rather rare.
Special Instructions:
Digoxin low dose (62.5 mcg / day or 125 mcg every other day) should be used on older people, patients with impaired renal function or patients with low body mass (lean).
Loading dose is not necessary in patients with congestive heart failure (CHF).
Avoid in patients with obstructive cardiomyopathy unless there is an acute heart failure, in patients with syndrome Wolff-Parkinson-White (WPW); not be used for ventricular arrhythmias.
Use with caution in cases of partial heart barrier, impaired trunk sinus, acute myocarditis, MI (myocardial infarction) acute, severe heart failure, acute pulmonary disease, in patients undergoing cardioversion (consider stopping cardioversion within 1-2 days prior to the procedure done) and with other drugs that can suppress the function of sinus and AV nodal functions (eg, Amiodarone or beta-blockers).
Hypokalemia, hyperkalemia, hipomagnesemia, hypoxia, and hyperthyroidism can affect sensitivity to digoxin.
Supervision is only required if the level of digoxin toxicity is suspected.
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